Enalaprilat Dihydrate

CAS No. 84680-54-6

Enalaprilat Dihydrate( —— )

Catalog No. M16146 CAS No. 84680-54-6

Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 30 In Stock
50MG 42 In Stock
100MG 76 In Stock
200MG 128 In Stock
500MG 310 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Enalaprilat Dihydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
  • Description
    Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.(In Vitro):Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.(In Vivo):Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
  • In Vitro
    Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
  • In Vivo
    Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    RAAS
  • Recptor
    ACE
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    84680-54-6
  • Formula Weight
    348.4
  • Molecular Formula
    C18H24N2O5.2H2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:70 mg/mL (200.91 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    O.O.C[C@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O |r,c:8,10,t:6|
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ceconi C, et al. Eur J Pharmacol, 2007, 577(1-3), 1-6.
molnova catalog
related products
  • N-Acetyl-Ser-Asp-Lys...

    Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice.N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) is a specific substrate for the N-terminal site of ACE and increases 5-fold during ACE inhibitor therapy.??AcSDKP inhibited the proliferation of isolated cardiac fibroblasts (P<0.05) but significantly stimulated the proliferation of vascular smooth muscle cells.?

  • Leucylarginylproline

    Leucylarginylproline is an?inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).

  • Angiotensin IV

    Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.