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Enalaprilat Dihydrate
CAS No. 84680-54-6
Enalaprilat Dihydrate( —— )
Catalog No. M16146 CAS No. 84680-54-6
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 30 | In Stock |
|
| 50MG | 42 | In Stock |
|
| 100MG | 76 | In Stock |
|
| 200MG | 128 | In Stock |
|
| 500MG | 310 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEnalaprilat Dihydrate
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NoteResearch use only, not for human use.
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Brief DescriptionEnalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
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DescriptionEnalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.(In Vitro):Enalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.(In Vivo):Enalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
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In VitroEnalaprilat (1 nM-10 μM; 24 h) dihydrate attenuates the IGF-I induced neonatal rat cardiac fibroblast growth (30% reduction) in a concentration-dependent fashion, with an IC50 of 90 mM.
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In VivoEnalaprilat (0.01%-2.9% in the eyedrop solution) dihydrate shows significant intraocular pressure (IOP)-lowering effect in rabbits.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorACE
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number84680-54-6
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Formula Weight348.4
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Molecular FormulaC18H24N2O5.2H2O
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Purity>98% (HPLC)
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SolubilityDMSO:70 mg/mL (200.91 mM)； Ethanol:<1 mg/mL (<1 mM)； Water:<1 mg/mL (<1 mM)
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SMILESO.O.C[C@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O |r,c:8,10,t:6|
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ceconi C, et al. Eur J Pharmacol, 2007, 577(1-3), 1-6.
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